Elucidating Genes Involved in the Pathogenesis of Lichen Planus and Lichenoid Dermatoses
We are investigating the pathogenesis of lichen planus (LP) and other lichenoid dermatoses using single-cell RNA sequencing and similar techniques on fresh lesional and nonlesional skin biopsies from patients. We will identify relevant cell types, proteins, and signaling pathways that may be responsible for driving disease, and confirm our findings in vitro with the ultimate goal of identifying novel therapeutic targets for these conditions.
— Anna E. Kersh, M.D., Ph.D.
- University of Pennsylvania
- Dermatologist Investigator Research Fellowship
Categories: Featured Researchers
Tags: 2021 Research Awards, Auto-immunity, Genetic Diseases and Gene Therapy, Inflammation
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