Auto-immunity

Elucidating Genes Involved in the Pathogenesis of Lichen Planus and Lichenoid Dermatoses

We are investigating the pathogenesis of lichen planus (LP) and other lichenoid dermatoses using single-cell RNA sequencing and similar techniques on fresh lesional and nonlesional skin biopsies from patients. We…

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Galen Foulke M.D.

Closing Practice Gaps in Dermatomyositis Malignancy Screening

Dermatomyositis is an autoimmune disease affecting skin and muscle, and 15%–20% of patients eventually develop cancer. Lack of evidence-based guidelines for malignancy screening represents a practice gap in dermatology and…

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Steven Chen M.D.

Investigation of Dermatologic Toxicity from Immune Checkpoint Blockade in Advanced Malignancies

Advanced malignancies are increasingly being treated with immune checkpoint inhibitors, which can lead to immune-related adverse events (irAEs), including those in the skin. This project will investigate key clinical, pathologic,…

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