Investigating Neuroimmune Interactions to Promote Scarless Skin Regeneration
Approximately 100 million new skin scars appear annually in the U.S. The many products marketed for scar prevention produce only modest results. We discovered that activation of the TRPA1 receptor on sensory neurons promotes scarless skin regeneration in mice. This current project aims to decipher molecular mechanisms controlling scar formation and skin regeneration in mammals, then identify new strategies to prevent scar formation in humans.
— Satish Sati, Ph.D.
- University of Pennsylvania
- Research Career Development Award
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