Closing Practice Gaps in Dermatomyositis Malignancy Screening
Dermatomyositis is an autoimmune disease affecting skin and muscle, and 15%–20% of patients eventually develop cancer. Lack of evidence-based guidelines for malignancy screening represents a practice gap in dermatology and rheumatology. This project aims to qualify the effectiveness of age-appropriate cancer screenings, define costs of advanced screening techniques, and launch development of a collaborative prospective registry aimed at defining best practices for malignancy screening in dermatomyositis.
— Galen Toye Foulke, M.D.
- UNC School of Medicine
- Medical Dermatology Career Development Award
Exploring Gene Expression Patterns and Biomarkers of Disease Severity in Central Centrifugal Cicatricial Alopecia
Central centrifugal cicatricial alopecia (CCCA), which has been associated with uterine fibroids, is unlike other scarring alopecias because fibrosis rather…
Vulvar lichen sclerosus is a chronic inflammatory condition that leads to scarring, obliteration of normal vulvar architecture, dyspareunia, and significant…
Cell Signaling Changes Induced by Surgical Debulking May Improve Response to Smoothened Inhibitor Therapy
Smoothened (SMO) inhibitors, such as vismodegib, are effective treatments for locally advanced basal cell carcinomas (BCCs). However, recurrences are frequent…