Assessing the Functional Consequences of Mitochondrial Genomic Alterations in Cutaneous Aging
Mitochondria generate energy for cells. They contain their own genome, which supports their function. Photoaging is associated with alterations to this genome, but the effects of these changes on mitochondrial function and clinical photoaging remain unclear. In this work, I will use cells with mitochondrial genome changes and histochemical markers of mitochondrial dysfunction to understand the relationship between the mitochondrial genome, mitochondrial function, and photoaging.
— Amy Ruth Vandiver, M.D., Ph.D.
- University of California, Los Angeles
- Dermatologist Investigator Research Fellowship
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