Optimizing Phototesting and Investigating Photobiology of Visible Light
Through improved means of investigating photoprotection efficacy extending into the visible waveband, the proposed studies should provide improved guidelines for testing sun protection agents that prevent sunburn in light-skinned individuals. Additionally, the understanding of the evolution of visible-light–induced pigmentation should improve the assessment and development of novel agents to prevent and treat hyperpigmentation skin conditions commonly seen in individuals with skin of color.
— Indermeet Kohli, Ph.D.
- Henry Ford Health System
- Research Career Development Award
Exploring Gene Expression Patterns and Biomarkers of Disease Severity in Central Centrifugal Cicatricial Alopecia
Central centrifugal cicatricial alopecia (CCCA), which has been associated with uterine fibroids, is unlike other scarring alopecias because fibrosis rather…
Vulvar lichen sclerosus is a chronic inflammatory condition that leads to scarring, obliteration of normal vulvar architecture, dyspareunia, and significant…
Cell Signaling Changes Induced by Surgical Debulking May Improve Response to Smoothened Inhibitor Therapy
Smoothened (SMO) inhibitors, such as vismodegib, are effective treatments for locally advanced basal cell carcinomas (BCCs). However, recurrences are frequent…