Skin Microbiome — Aryl Hydrocarbon Receptor Crosstalk at Skin Interface Regulates Barrier Function
A compromised skin barrier results in increased susceptibility to pathogens and chronic conditions (e.g., atopic dermatitis) that severely impact human appearance. The skin microbiome is a critical regulator of skin physiology. However, the chemical diversity of signals from skin microbes, and how keratinocytes decipher them, remain unexplored. Our goal is to understand how host–microbiota interactions regulate skin barrier integrity.
— Aayushi Uberoi, Ph.D.
- University of Pennsylvania
- Science of Human Appearance Career Development Award
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