Auto-immunity
Elucidating Genes Involved in the Pathogenesis of Lichen Planus and Lichenoid Dermatoses
We are investigating the pathogenesis of lichen planus (LP) and other lichenoid dermatoses using single-cell RNA sequencing and similar techniques on fresh lesional and nonlesional skin biopsies from patients. We…
Closing Practice Gaps in Dermatomyositis Malignancy Screening
Dermatomyositis is an autoimmune disease affecting skin and muscle, and 15%–20% of patients eventually develop cancer. Lack of evidence-based guidelines for malignancy screening represents a practice gap in dermatology and…
Investigation of Dermatologic Toxicity from Immune Checkpoint Blockade in Advanced Malignancies
Advanced malignancies are increasingly being treated with immune checkpoint inhibitors, which can lead to immune-related adverse events (irAEs), including those in the skin. This project will investigate key clinical, pathologic,…