Melanoma
Loss of Effective Antigen Presentation in Melanoma and Treatment Failure
Loss of effective presentation of tumor antigens by melanoma may drive immunotherapy resistance. We will use multiplex immunofluorescence to map antigen presentation at single-cell resolution across whole slides, and correlate…
Preventing Metastasis of High-Risk Melanoma
In the U.S., more than 7,000 people die from melanoma annually. Up to one-third of these deaths are caused by early, localized melanomas (AJCC Stage 1–2) that metastasize despite appropriate…